Standard operation codes contain x"FA" in the most significant byte. The least significant byte indicates the specific operation.
| CLOSE | Terminates the processing of a file. | 
| COMMIT | Releases all record locks in all files held by a run unit. | 
| DELETE | Logically removes a record from a file. | 
| DELETE FILE | Physically removes the specified file from the physical devices on which it resides. | 
| OPEN | Initiates the processing of files. It also performs checking and/or writing of labels and other I/O operations. | 
| READ | For sequential access, makes available the next or previous logical record from a file. For random access, makes available a specified record from a disk file. | 
| ROLLBACK | Releases all record locks in all files held by a run unit. | 
| START | Provides a basis for logical positioning in a relative or indexed file, for subsequent retrieval of records. | 
| STEP | Steps to the next physical record. | 
| UNLOCK | Releases all record locks held by a run unit on a named file. | 
| WRITE | Writes a new record to a file. | 
| REWRITE | Replaces an existing record. | 
Not all operation codes are appropriate with all file organizations. Each operation code description includes a list of the file organizations for which it is valid, using the following key:
| L | Line sequential | 
| S | Record sequential (including vS) | 
| R | Relative (including vR) | 
| I | Indexed | 
| vS | Record sequential variable format only | 
| vR | Relative variable format only |